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- Howard A Cooper and Julio A Panza.
- Coronary Care Unit, Medstar Heart Institute, Medstar Washington Hospital Center, 110 Irving Street Northwest, Suite NA-1103, Washington, DC 20010, USA. Electronic address: howard.a.cooper@medstar.net.
- Cardiol Clin. 2013 Nov 1;31(4):567-80, viii.
AbstractCardiogenic shock (CS) is a condition in which a marked reduction in cardiac output and inadequate end-organ perfusion results from an array of cardiac insults, the most common of which is acute myocardial infarction. CS is a systemic disease involving a vicious cycle of inflammation, ischemia, and progressive myocardial dysfunction, which often results in death. This life-threatening emergency requires intensive monitoring accompanied by aggressive hemodynamic support; other therapies are tailored to the specific pathophysiology. The development of novel therapeutic strategies is urgently required to reduce the unacceptably high mortality rates currently associated with CS.Copyright © 2013 Elsevier Inc. All rights reserved.
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