• Simon J Davidson, Donovan McGrowder, Michael Roughton, and Andrea A Kelleher.
• Department of Haematology, Royal Bromptom Hospital, London, UK. s.davidson@rbht.nhs.uk
• J. Cardiothorac. Vasc. Anesth. 2008 Oct 1;22(5):655-61.

ObjectiveTo evaluate the predictive ability of ROTEM thromboelastometry (Pentapharm, Basel, Switzerland) to identify patients bleeding more than 200 mL/h in the early postoperative period after cardiac surgery.DesignA prospective observational study.SettingA single university hospital.ParticipantsFifty-eight adult male and female patients undergoing primary coronary artery revascularization.InterventionsBlood samples taken preoperatively and at 1, 2, and 3 hours after surgery.Measurements And Main ResultsEight patients bled at least 200 mL/h in the study period. All (100%) had at least 1 abnormal ROTEM result in the study period. Of the 49 patients not found to be bleeding more than 200 mL/h in any of the first 4 postoperative hours, 46 (94%) had at least 1 abnormal ROTEM result. The positive and negative predictive values were 14.8% and 100%, respectively.ConclusionsROTEM thromboelastometry has poor predictive utility to identify patients who bleed more than 200 mL/h in the early postoperative period after cardiac surgery. However, its negative predictive value was good.

14 keywords...

hide…