• BJOG · Jan 2006

    Randomized Controlled Trial

    Intrauterine lignocaine as an anaesthetic during endometrial sampling: a randomised double-blind controlled trial.

    • S K Hui, L Lee, C Ong, V Yu, and L C Ho.
    • Department of Obstetrics and Gynaecology, Princess Margaret Hospital, Hong Kong, China.
    • BJOG. 2006 Jan 1;113(1):53-7.

    ObjectiveTo evaluate the effectiveness of intrauterine lignocaine as an anaesthetic during endometrial sampling.DesignProspective, randomised, double-blind, placebo-controlled trial.SettingOutpatient gynaecological minor operation unit in a public hospital.PopulationTwo hundred premenopausal women scheduled for endometrial sampling because of abnormal uterine bleeding.MethodsTranscervical intrauterine instillation of 5 mL of 2% lignocaine or 5 mL of normal saline before performing endometrial sampling with vacuum aspirator.Main Outcome MeasuresEvaluation of pain associated with the procedure using a visual analogue scale.ResultsThe use of intrauterine lignocaine reduced pain during suction curettage in endometrial sampling.ConclusionsTranscervical instillation of lignocaine reduced pain during endometrial sampling.

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