• Indian J Pediatr · Oct 2009

    Case Reports

    Locked-in syndrome: A rare manifestation of pediatric stroke.

    • Monica Juneja, Rahul Jain, Swati Singhal, Devendra Mishra, and Sapna Singh.
    • Department of Pediatric, Maulana Azad Medical College and Associated Lok Nayak Hospital, Bahadur Shah Zafar Marg, New Delhi, India.
    • Indian J Pediatr. 2009 Oct 1;76(10):1053-5.

    AbstractLocked-in syndrome is characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral horizontal gaze palsy and anarthria, with preserved consciousness. It is due to a ventral pontine lesion following a basilar artery occlusion. We report the first Indian case report of locked-in syndrome, a 10-year old girl in whom the syndome was preceded by a 'herald hemiparesis'. Although the exact etiology for the basilar artery occlusion could not be determined, treatment with low molecular weight heparin and warfarin was followed by partial recovery.

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