-
Multicenter Study Comparative Study
The use of APACHE III to evaluate ICU length of stay, resource use, and mortality after coronary artery by-pass surgery.
- R B Becker, J E Zimmerman, W A Knaus, D P Wagner, M G Seneff, E A Draper, T L Higgins, F G Estafanous, and F D Loop.
- Department of Anesthesiology, George Washington University Medical Center, Washington, DC 20037, USA.
- J Cardiovasc Surg. 1995 Feb 1;36(1):1-11.
ObjectiveTo identify patient characteristics that are associated with increased ICU length of stay, resource use, and hospital mortality after coronary artery bypass surgery.DesignProspective, multicenter study.SettingSix tertiary care hospitals.ParticipantsA consecutive sample of 2,435 unselected ICU admissions following coronary artery by-pass surgery.Materials And MethodsDemographic, operative characteristics and APACHE III score were collected during the first postoperative day; and APACHE III scores and therapeutic interventions during the first three postoperative days. Hospital survival and ICU length of stay were also recorded. Multivariate equations were derived and cross-validated to predict hospital mortality, ICU length of stay, and ICU resource use.ResultsUnadjusted hospital mortality rate was 3.9% (range 1.0% to 6.0%), mean ICU length of stay was 3.7 days (range 3.2 to 4.7 days), and first 3-day ICU resource use (TISS points) was 99 (range 68 to 116). The range of actual to predicted ICU length of stay varied from 0.86 to 1.26; and resource use from 0.71 to 1.16.ConclusionsA limited number of operative characteristics, the post-operative acute physiology score (APS) of APACHE III and patient demographic data can predict hospital death rate, ICU length of stay, and resource use immediately following coronary by-pass surgery. These estimates may compliment assessments based on pre-operative risk factors in order to more precisely evaluate and improve the efficacy and efficiency of cardiovascular surgery.
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