• La Tunisie médicale · Sep 2009

    Comparative Study

    Risk factors of fetal macrosomia: role of maternal nutrition.

    • Walid Denguezli, Raja Faleh, Anissa Fessi, Alaeddine Yassine, Awatef Hajjaji, Hayett Laajili, and Mohamed Sakouhi.
    • Department of Obstetric and Gynaecology, University Hospital Fattouma Bourguiba, Monastir, Tunisia.
    • Tunis Med. 2009 Sep 1;87(9):564-8.

    AimTo assess the effect of maternal diet during pregnancy on the risk of delivering a large for gestational baby (macrosome).MethodsA food intake survey of 350 healthy pregnant Tunisian women, 52 in group macrosomia and 298 in group control. Only term (> or =37 completed Weeks of gestation) infants were included. All women in the study group completed food frequency questionnaires on their diet in the last 24 hours before delivery.ResultsFrequency of foetal macrosomia was 15.8% (n=52). Pregravid maternal BMI >30 (OR = 3.06 [1.51-6.17]), prolonged term of pregnancy (> 41 weeks of gestation) (OR = 249 [1.04-5.88]) and the antecedent of a macrosomic delivery (OR = 6.53 [2.89-14.74]) were significantly associated with the risk of fetal macrosomia. The mean daily total energetic intakes, protein intakes and carbohydrate intakes were significantly higher in the macrosomia group than in the control group. However, with multivariate analysis after adjustment for term and Pregravid BMI, no significant correlation was found between nutrient intakes and risk of fetal macrosomia.ConclusionMaternal food intakes in the end of pregnancy are not a significant determinant of fetal macrosomia compared to maternal BMI, and term of pregnancy.

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