• Chinese Med J Peking · Aug 2011

    Review Case Reports

    Docetaxel-induced nail toxicity: a case of severe onycholysis and topic review.

    • Chi-Pan Lau, Pun Hui, and Tak-Cheung Chan.
    • Department of Clinical Oncology, Prince of Wales Hospital, Shatin, Ngan Shing Street, New Territories, Hong Kong, China. patricklau75@hotmail.com
    • Chinese Med J Peking. 2011 Aug 1;124(16):2559-60.

    AbstractDocetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.

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