• Duodecim · Jan 2014

    Review

    [Imaging of brain changes in chronic pain].

    • Nuutti Vartiainen and Nina Forss.
    • Duodecim. 2014 Jan 1;130(15):1507-14.

    AbstractModern methods of brain imaging have enabled objective measurements of functional and structural brain changes associated with chronic pain conditions. According to recent investigations, chronic pain is not only associated with abnormally strong or prolonged activity of regions processing acute pain, but also with activation of brain networks that are characteristic for each pain state, changes in cortical remodeling, as well as local reduction of grey matter in several regions of the brain. Brain changes associated with chronic pain facilitate the understanding of mechanisms of various chronic pain conditions.

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