• Middle East J Anaesthesiol · Oct 2009

    Randomized Controlled Trial Comparative Study

    Oxygenation during one-lung ventilation with propofol or sevoflurane.

    • Konrad Schwarzkopf, Lars Hueter, Torsten Schreiber, Niels-Peter Preussler, Volker Loeb, and Waheedullah Karzai.
    • Department of Anesthesiology and Intensive Care Medicine, Klinikum Saarbrueken, Winterberg 1, 66119 Saarbruecken, Germany. kschwarzkopf@klinikum-saarbruecken.de
    • Middle East J Anaesthesiol. 2009 Oct 1;20(3):397-400.

    Abstract60 patients, ASA I-III, underwent one-lung ventilation for open or video-assisted thoracic surgery randomized either with intravenous anesthesia with propofol or with inhalational anesthesia with 1 MAC sevoflurane. Propofol was titrated during one-lung ventilation to achieve a mean arterial pressure of 75-80 mmHg. Blood gas analyses, hemodynamic and respiratory parameters were measured during two-lung ventilation at the beginning of the surgical procedure and 10 min, 20 min and 30 min after start of one-lung ventilation. At all time points, hemodynamic and respiratory parameters were comparable in both groups. Oxygenation did not differ between groups at comparable mean arterial blood pressures.

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