• The Journal of pediatrics · Mar 2001

    Case Reports

    Ophthalmic drops causing coma in an infant.

    • R J Berlin, U T Lee, J R Samples, L F Rich, D D Tang-Liu, K A Sing, and R D Steiner.
    • Oregon Poison Center, Department of Emergency Medicine, Oregon Health Sciences University, Portland, 97207, USA.
    • J. Pediatr. 2001 Mar 1;138(3):441-3.

    AbstractA 1-month-old infant with Peters anomaly had recurrent episodes of unresponsiveness, hypotension, hypotonia, hypothermia, and bradycardia. An extensive medical evaluation determined these episodes to be caused by brimonidine, an anti-glaucoma agent. There is the potential for serious toxic effects from the systemic absorption of topically applied ophthalmic agents in children.

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