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- Carles Vallvé, Maite Artés, Erik Cobo, and TREND group.
- Farmacólogo clínico, Cardedeu, Barcelona, España. vallve@telefonica.net
- Med Clin Barcelona. 2005 Dec 1;125 Suppl 1:38-42.
AbstractNonrandomized intervention trials are needed when randomized clinical trials cannot be performed. To report the results from nonrandomized intervention studies transparently, the TREND (Transparent Reporting of Evaluations with Nonrandomized Designs) checklist should be used. This implies that nonrandomized studies should follow the remaining methodological tools usually employed in randomized trials and that the uncertainty introduced by the allocation mechanism should be explicitly reported and, if possible, quantified.
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