• Anasthesiol Intensivmed Notfallmed Schmerzther · Nov 2015

    Review

    [Coagulation factor XIII - Pathophysiology, clinic and therapy of factor XIII deficiency].

    • Christian Friedrich Weber, Elisabeth Hannah Adam, Andreas Pape, Marina Jöst, Patrick Meybohm, Katja Schmitz, Kai Zacharowski, Martin Hermann, and Dietmar Fries.
    • Anasthesiol Intensivmed Notfallmed Schmerzther. 2015 Nov 1; 50 (11-12): 684-90.

    AbstractThe complex activity of the transglutaminase factor XIII (FXIII) comprises central functions in secondary hemostasis. Congenital or acquired FXIII deficiencies may be associated with habitual abortions, impaired wound healing, coagulopathy and fatal hemorrhage. The present review describes physiological functions of FXIII, as well as pathophysiology, diagnostic and therapeutic options of FXIII deficiencies.

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