• J Laparoendosc Adv Surg Tech A · Feb 1999

    Randomized Controlled Trial Clinical Trial

    Nausea and vomiting after laparoscopic gynecological surgery: a study of the incidence and the effects of tropisetron prophylaxis.

    • J Jakobsson, G Dahlgren, E Oddby, and G Ryberg.
    • Department of Anaesthesia, Sabbatsberg Närsjukhuset, Sweden.
    • J Laparoendosc Adv Surg Tech A. 1999 Feb 1;9(1):51-5.

    AbstractThe authors studied the incidence of postoperative nausea and vomiting (PONV) and the effect of prophylactic tropisetron, a 5-HT3 antagonist, during the first 24 h following elective gynecologic laparoscopic surgery. Thirty-two of 68 (47%) of the patients experienced nausea or vomiting some time during the observation period. Sixteen of the 32 PONV patients (50%) had their first emetic symptoms after discharge from the recovery room. We could see no difference in the frequency of PONV in the patients who were given prophylactic tropisetron 5 mg orally before anesthesia.

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