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- Andrew M Redmond, Tina Skinner-Adams, Katherine T Andrews, Donald L Gardiner, John Ray, Mark Kelly, and James S McCarthy.
- Department of Infectious Diseases, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
- AIDS. 2007 Mar 30;21(6):763-5.
AbstractSynergy between HIV and malaria is being increasingly recognized. We examined the antimalarial activity of sera from subjects receiving chloroquine, no drugs or HAART. Sera from subjects taking ritonavir-boosted saquinavir or lopinavir significantly inhibited parasite growth (median of 55 and 69% inhibition, respectively). These results indicate that patients on protease inhibitors may be afforded some protection from malaria. The clinical relevance of these observations will require confirmation in controlled studies in malaria-endemic regions.
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