• Iris Iglesia, Theodora Mouratidou, Marcela González-Gross, Romana Novakovic, Christina Breidenassel, David Jiménez-Pavón, Inge Huybrechts, Stefaan De Henauw, Anouk Geelen, Frédéric Gottrand, Anthony Kafatos, Lorenza Mistura, Fátima Pérez de Heredia, Kurt Widhalm, Yanis Manios, Denes Molnar, Peter Stehle, Mirjana Gurinovic, Adrienne E J M Cavelaars, Pieter Van't Veer, Luis A Moreno, and HELENA study group.
• GENUD: "Growth, Exercise, Nutrition and Development" Research Group, University of Zaragoza, Zaragoza, Spain; Faculty of Health Sciences, University of Zaragoza, Zaragoza, Spain.
• Nutr Res. 2014 Mar 1;34(3):199-209.

AbstractBecause socioeconomic factors (SEFs) may influence dietary quality and vitamin intakes, this study aimed to examine associations between socioeconomic factors and folate and vitamin B12 intakes as well as their related biomarkers in the Healthy Lifestyle in Europe by Nutrition in Adolescence study. Vitamin intakes were obtained from two 24-hour recalls in 2253 participants (47% males). Vitamin B biomarkers were assessed in a subsample of 977 participants (46% males). Socioeconomic factors were assessed by questionnaire, and 1-way analysis of covariance and linear regression analysis were applied. For males and females, mean intakes of folate were 211.19 and 177.18 μg/d, and for vitamin B12, 5.98 and 4.54 μg/d, respectively. Levels of plasma folate, red blood cell folate, serum B12, and holotranscobalamin were 18.74, 807.19, 330.64, and 63.04 nmol/L in males, respectively, and 19.13, 770.16, 377.9, and 65.63 nmol/L in females, respectively. Lower folate intakes were associated with several SEFs, including maternal and paternal education in both sexes. Regarding folate biomarkers, lower plasma folate intakes were associated with single/shared care in males and with lower paternal occupation in females. Lower vitamin B12 intakes were associated with almost all the studied SEFs, except paternal occupation in both sexes. In females, when considering vitamin B12 biomarkers, lower plasma vitamin B12 was associated with lower maternal education and occupation, and lower holotranscobalamin was associated with lower maternal education and lower paternal occupation. In conclusion, from the set of socioeconomic determinants studied in a sample of European adolescents, maternal education and paternal occupation were more consistently associated with folate and vitamin B12 intakes and biomarkers concentrations.Copyright © 2014 Elsevier Inc. All rights reserved.

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