• Paediatric anaesthesia · Nov 2003

    Case Reports

    Lacticacidosis after short-term infusion of propofol for anaesthesia in a child with osteogenesis imperfecta.

    • Clemens Kill, Andreas Leonhardt, and Hinnerk Wulf.
    • Department of Anaesthesiology and Intensive Care Medicine, Philipps-University, Marburg, Germany. killc@mailer.uni-marburg.de
    • Paediatr Anaesth. 2003 Nov 1; 13 (9): 823-6.

    AbstractWe describe the case of a 7-year-old boy with osteogenesis imperfecta, who underwent anaesthesia with propofol-fentanyl-nitrous oxide-suxamethonium for orthopaedic surgery of a distal femur fracture. He developed lacticacidosis after short-term propofol infusion (150 min, mean infusion rate 13.5 mg.kg-1.h-1) associated with a prolonged recovery time without serious haemodynamic changes. The highest lactate concentration was 9.2 mmol.l-1 at 160 min after discontinuation of propofol. There was no significant increase in body temperature. The boy fully recovered.

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