• Stefan Kissler, Marianne Haas, Renate Strohmeier, Hubert Schmitt, Achim Rody, Manfred Kaufmann, and Ernst Siebzehnruebl.
• Division of Gynecologic Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany.
• J Am Assoc Gynecol Laparosc. 2004 Nov 1;11(4):473-7.

Study ObjectiveTo determine the effect of humidified and heated CO(2) for pneumoperitoneum during laparoscopic surgery on analgesic requirements, postoperative pain, and patient satisfaction.DesignProspective, randomized, double-blind, controlled study (Canadian Task Force classification I).SettingUniversity hospital.PatientsNinety consecutive women scheduled for gynecologic laparoscopic surgery.InterventionOperative laparoscopic management of adnexa surgery or adhesiolysis.Measurements And Main ResultsThirty consecutive patients were randomized into each study group. Group I received humidified, heated gas; group II dry, heated gas; and group III (control group) standard dry, cold gas. No significant difference in intraoperative and postoperative analgesic requirements or postoperative pain score between group I and group II was found. There was even a tendency (not significant) toward less pain and higher postoperative satisfaction in patients in the control group. Therefore, the evaluation was stopped after 53 patients.ConclusionThe use of humidified, heated gas did not reduce postoperative pain or intraoperative analgesic requirements and is thus not preferable to standard dry, cold gas in gynecologic laparoscopic surgery.

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