• J. Neurol. Neurosurg. Psychiatr. · Feb 2012

    Convergence spasm in conversion disorders: prevalence in psychogenic and other movement disorders compared with controls.

    • Robert Fekete, Jose Fidel Baizabal-Carvallo, Ainhi D Ha, Anthony Davidson, and Joseph Jankovic.
    • Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, The Smith Tower, Suite 1801, 6550 Fannin St Houston, TX 77030, USA. robertfekete@hotmail.com
    • J. Neurol. Neurosurg. Psychiatr. 2012 Feb 1;83(2):202-4.

    BackgroundConvergence spasm refers to transient ocular convergence, miosis and accommodation associated with disconjugate gaze mimicking abducens palsy. While it may be a manifestation of brainstem pathology, this sign is often associated with conversion (somatisation) disorders and, if unrecognised as a sign of a psychogenic disorder, it may lead to unnecessary and occasionally invasive evaluation.MethodsTo better characterise this neuro-ophthalmologic sign, 36 subjects were studied, 13 with psychogenic movement disorders, 11 with organic movement disorders and 12 normal controls. Patients were recorded during a manoeuvre to elicit convergence spasm and the videotapes were rated by two blinded raters on a scale of 0=normal, 1=mild convergence spasm and 2=marked convergence spasm.ResultsConvergence spasm was present in 9/13 (69%) psychogenic movement disorders cases, 4/11 (36%) non-psychogenic movement disorders cases and 4/12 (33%) controls (p=0.049 when psychogenic vs non-psychogenic disorders or controls were compared). Inter-rater reliability analysis of the presence (rating 1 or 2) versus absence (rating 0) showed good agreement (27/36 or 75%; kappa 0.491, SE 0.141, p=0.002). Analysis for the presence of marked convergence spasm (rating 2) yielded agreement in 32/36 (88.9%) examinations (kappa 0.652, SE 0.154, p<0.001) with a specificity of 87% (sensitivity 15%).ConclusionConvergence spasm may provide benefit in the clinical examination of psychogenic movement disorders patients.

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