• Ulrich Quast, Theodor W Kaulich, and Joachim Lorenz.
• Abteilung Strahlentherapie, Klinische Strahlenphysik, Universitätsklinikum Essen. ulrich.quast@uni-essen.de
• Herz. 2002 Feb 1;27(1):7-16.

BackgroundThe success of intravascular brachytherapy relies entirely on the interdisciplinary approach. Interventional cardiologists, radiation oncologists and medical physicists must form a team from day 1. All members of the team need special knowledge and regular training in the field of vascular radiation therapy. Optimization of intravascular brachytherapy requires the use of standardized methods of dose specification, recording and reporting. This also implies using standardized methods of source calibration in terms of absorbed dose to water and having methods for simple internal control of the dosimetric quantities of new or replaced sources. Guidance is offered by international recommendations (AAPM TG 60, DGMP Report 16, NCS and EVA GEC-ESTRO). LEGAL REQUIREMENTS FOR RADIATION PROTECTION--WHAT'S NEW?: In Europe, new legal requirements on radiation protection issues have to be fulfilled. For Germany, the revised "Strahlenschutzverordnung" has been released recently. Nearly all organizational and medical processes are affected. For intravascular brachytherapy, several changes of requirements have to be considered. However, to follow these requirements does not cause serious problems. DGMP REPORT 16: GUIDELINES FOR MEDICAL PHYSICAL ASPECTS OF INTRAVASCULAR BRACHYTHERAPY: Evaluation of clinical results by comparison of intravascular brachytherapy treatment parameters is possible only if the prescribed dose and the applied dose distribution are reported clearly, completely and uniformly. The DGMP guidelines thus recommend to prescribe the dose to water at the system related reference point PRef at 2 mm radial distance for intracoronary application (and at 5 mm for peripheral vessels). The mean dose at 1 mm tissue depth (respectively at 2 mm) should be reported in addition. To safely define the planning target volume from the injured length, safety margins of at least 5 mm (10 mm) have to be taken into account on both ends. Safety margins have also to be considered for multisegmental treatment, to omit underdosage. IVUS based localization will support precise planning, avoid a geographic miss and edge effects and will allow for later evaluation. These DGMP recommendations are also included in the EVA GEC ESTRO recommendations and in the draft for an up-date of the AAPM TG 60 report.ConclusionMedical physical quality management of intravascular brachytherapy is a necessary condition for optimal and safe treatment. Procedures, devices, and sources should fulfill the same degree of precision and safety as common in radiotherapy.

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