• Martina Fanella, Alessandra Morano, Jinane Fattouch, Mariarita Albini, Sara Casciato, Mario Manfredi, Anna Teresa Giallonardo, and Carlo Di Bonaventura.
• Department of Neuroscience, Neurology Unit, "Sapienza" University, Rome, Italy.
• J Headache Pain. 2015 Jan 1; 16: 105.

AbstractEpileptic seizures and headache attacks are two common neurologic phenomena characterized by paroxysmal alteration of brain functions followed by complete restauration of the baseline condition. Headache and epilepsy are related in numerous ways, and they often co-occur. Although the link between these two diseases is not completely clear, several clinical, physiopathological and therapeutic features overlap. Headache is reported in association with epileptic seizures as a pre-ictal, ictal or post-ictal phenomenon. We present the case of a 40 year-old woman affected by eyelid myoclonia with absences (EMA) with a history of prolonged headache attacks. A video-EEG recording performed during one of these episodes showed subcontinuous epileptic activity consisting of generalized spike-and-wave discharges (GSWDs), clinically associated with tensive headache. Our work represents one of the few well EEG-documented cases of ictal epileptic headache in idiopathic generalized epilepsy (IGE).

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