• M Chulay, J Palmer, J Neblett, A R Nancherla, D Tripodi, and D Caden.
• Critical Care Nursing Service, Warren Grant Magnuson Clinical Center, Bethesda, MD.
• Am. J. Crit. Care. 1992 Jul 1;1(1):69-75.

ObjectiveTo evaluate clinically the accuracy of continuous SvO2 systems to reflect reference SvO2 values over a 24-hour period.DesignRandomized clinical trial.SettingSix-bed cardiac surgical intensive care unit of a 540-bed federal facility.PopulationSixty postoperative cardiac patients.InterventionsRandom assignment to a two- or three-wavelength continuous SvO2 catheter for postoperative SvO2 monitoring. At 4-hour intervals over a 24-hour period, mixed venous blood samples were analyzed with a reference cooximeter and compared with the monitor value of the SvO2 catheter.Main Outcome MeasuresA reference cooximeter method to measure SvO2 in mixed venous blood; SvO2 as measured by the in-line, SvO2 catheter system.ResultsSvO2 measured by the three-wavelength system did not differ significantly from the reference SvO2 measurement. In contrast, SvO2 measured by the two-wavelength system was significantly lower than the reference SvO2 measurement within 4 hours of admission to the critical care unit and remained significantly lower throughout the 24-hour study period.ConclusionsThe results of this clinical study confirmed a previous study in dogs, showing that SvO2 is measured more accurately by the three-wavelength continuous monitoring system.

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