• Southern medical journal · Aug 2002

    Case Reports

    Hemothorax and retroperitoneal hematoma after anticoagulation with enoxaparin.

    • Michal Mrug, Prashant V Mishra, Henry C Lusane, J Martin Cunningham, and Martin A Alpert.
    • Department of Internal Medicine, University of South Alabama College of Medicine, Mobile, USA.
    • South. Med. J. 2002 Aug 1;95(8):936-8.

    AbstractA 58-year-old woman with chronic obstructive pulmonary disease had spontaneous bilateral hemothorax and a retroperitoneal hematoma after 4 days of anticoagulation therapy with enoxaparin (1 mg/kg subcutaneously every 12 hours) for suspected pulmonary thromboembolism. The patient was successfully managed with red blood cell and plasma transfusions, multiple thoracenteses for evacuation of blood from the pleural space, short-term mechanical ventilation, and administration of bronchodilators, corticosteroids, and antibiotics. This is the first report of spontaneous hemothorax and the third report of spontaneous retroperitoneal hematoma associated with enoxaparin therapy.

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