• Vanessa K Noonan, Jacek A Kopec, Hongbin Zhang, and Marcel F Dvorak.
• Division of Spine, Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada. Vanessa.Noonan@vch.ca
• Arch Phys Med Rehabil. 2008 Jun 1;89(6):1074-82.

ObjectiveTo determine the effect of associated spinal cord injury (SCI) conditions on the health status and quality of life (QOL) in people with traumatic central cord syndrome.DesignCross-sectional design.SettingCommunity-based.ParticipantsSubjects (N=70) with traumatic central cord syndrome who were a minimum of 2 years postinjury.InterventionsNot applicable.Main Outcome MeasuresPresence of associated SCI conditions (neuropathic pain, spasticity, bowel, bladder, and/or sexual dysfunction, decreased motor function); health status (36-Item Short-Form Health Survey [SF-36], symptom satisfaction); and QOL.ResultsThe SF-36 physical component score (PCS) was lower in subjects who reported problems with bowel, bladder, and/or sexual function (-6.9; 95% confidence interval [CI], -11.6 to -2.2). The PCS was decreased in subjects with a lower motor score and this relationship was negatively affected by spasticity and being less educated. The SF-36 mental component score was negatively affected by neuropathic pain and a lower motor score. Neuropathic pain and a lower motor score were both associated with subjects being dissatisfied with their symptoms. Subjects who had a higher motor score were more likely to have a higher QOL (odds ratio, 1.7; 95% CI, 1.1 to 2.7).ConclusionsThe associated SCI conditions bowel, bladder, and/or sexual dysfunction, neuropathic pain, decreased motor function, and spasticity negatively affect the health status of persons with traumatic central cord syndrome. Diminished motor recovery was the only associated SCI condition to impact QOL. By developing a conceptual model and adjusting for confounders, an estimate for each associated SCI condition's effect on patient outcomes was obtained. Our results indicate the importance of treating or ameliorating associated SCI conditions in order to maximize physical and mental functioning.

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