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- B N Mukunda.
- Department of Medicine, Meridia Huron Hospital, Cleveland, Ohio 44112, USA.
- Am. J. Med. Sci. 1999 Apr 1;317(4):261-2.
BackgroundMetabolic acidosis from accumulation of lactic acid is a relatively common condition, whereas its causation by thiamine deficiency is not.MethodsWe studied a pregnant alcoholic patient who presented with hyperemesis and a high anion gap acidosis.ResultsLactic acidosis and thiamine deficiency were confirmed. The patient's symptoms and acidosis resolved with thiamine administration.ConclusionsLactic acidosis caused by thiamine deficiency must be suspected when pregnant patients at risk for thiamine deficiency present with a high anion gap acidosis. A large dose of thiamine must be administered immediately.
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