• Harefuah · Jul 2012

    Case Reports

    [Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].

    • Tamar Miller-Roll, Izabella Pilcha, Natan Weksler, Sorina Negomireanu, and Murat Bahar.
    • Department of Anesthesiology, Assaf Harofeh Medical Center, Zerifin, Israel.
    • Harefuah. 2012 Jul 1;151(7):402-4, 436.

    AbstractA 30 years old parturient was admitted to the operating theatre for revision of uterus after spontaneous labor because of hemorrhage. She underwent general anesthesia induced by rapid sequence induction (RSI) technique. Apnea for 45 minutes was observed after succinylcholine administration. Biochemistry laboratory tests from the operation day showed very low butyrylcholinesterase activity, and a repeated test after one month showed normal enzyme activity and inhibitors within the normal range. Genetic tests revealed heterozygosity for the K variant of BChE. This may explain the increased sensitivity to succinylcholine during pregnancy.

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