• Jian-qing Xu, Tie-hu Ye, Yu-guang Huang, and Ai-lun Luo.
• Department of Anesthesiology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. jqxu@163bj.com
• Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2010 Oct 1;32(5):569-73.

ObjectiveTo evaluate the value of propofol target-controlled infusion combined with dribbled and nebulized lidocaine in tracheal intubation under spontaneous breathing.MethodsTotally 40 elective surgery patients to accept tracheal intubation under unconsciousness and spontaneous breathing were randomly divided into 2 groups: 6-8 cm of endotracheal tube was inserted subglottic ally in the complete intubation group (n=20) while 3-4 cm was inserted temporarily in the partial intubation group (n=20).ResultsThe tracheal intubation was successfully completed under spontaneous breathing in all patients; meanwhile,the hemodynamic status was stable without any severe respiratory complications. Eleven patients suffered from moderate coughing response in the complete intubation group while no such response was noted in the partial intubation group (P<0.01).ConclusionsApplication of propofol target-controlled infusion combined with dribbled and nebulized lidocaine provides a good condition for tracheal intubation under unconsciousness and spontaneous breathing. The partial intubation can effectively prevent the occurrence of coughing response.

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