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Expert Opin Pharmacother · Oct 2006
ReviewManagement of sepsis in the critically ill patient: key aspects.
- Jean-Louis Vincent.
- Department of Intensive Care, Erasme University Hospital, Route de Lennik 808, B-1070 Brussels, Belgium. jlvincen@ulb.ac.be
- Expert Opin Pharmacother. 2006 Oct 1;7(15):2037-45.
AbstractSevere sepsis is a major cause of morbidity and mortality in the critically ill patient. Management involves identification and treatment of the underlying causative infection, with antimicrobial agents and surgery where necessary, haemodynamic resuscitation with fluids and vasoactive agents, steroids (for septic shock) and immunomodulation with drotrecogin-alpha (activated), where not contraindicated. Every effort must be made to identify sepsis early so as to optimise the patient's chances of a good outcome.
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