• Gastrointest. Endosc. Clin. N. Am. · Apr 2012

    Review

    Endoscopic ultrasound-guided celiac neurolysis.

    • Michael J Levy, Suresh T Chari, and Maurits J Wiersema.
    • Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. levy.michael@mayo.edu
    • Gastrointest. Endosc. Clin. N. Am. 2012 Apr 1;22(2):231-47, viii.

    AbstractIntractable abdominal pain commonly develops in patients with pancreatic cancer. Oral pharmacologic therapy is ineffective for many patients and side effects commonly occur. Celiac neurolysis (CN) is sometimes performed to enhance pain relief. Percutaneous approaches were initially described, with endoscopic ultrasound (EUS)-guided CN more recently introduced. There is uncertainty regarding the efficacy and role of CN in managing pancreatic cancer pain, but CN should still be considered in this difficult-to-treat cohort of patients. EUS-guided approaches may be favored when EUS is otherwise indicated for diagnostic or staging purposes. When EUS is not otherwise indicated, percutaneous approaches are likely favored.Copyright © 2012 Elsevier Inc. All rights reserved.

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