• Masui · Jul 2002

    Case Reports

    [Fentanyl administration during sevoflurane anesthesia suppresses spike waves from epileptic focus on electrocorticogram].

    • Shinichi Koyama, Yuriko Makino, Kazuo Tanaka, Michiharu Morino, Kiyonobu Nishikawa, and Akira Asada.
    • Department of Anesthesiology, Osaka City University Medical School, Osaka 545-8586.
    • Masui. 2002 Jul 1;51(7):755-8.

    AbstractA 36-year-old man with intractable epileptic seizures underwent insertion of subdural electrodes on bilateral temporal lobes under air-oxygen-sevoflurane anesthesia. After the completion of the operation, we measured electrocorticogram at end-tidal sevoflurane concentration of 2.5%, 1.5%, and 1.5% with 0.1 mg intravenous fentanyl. When sevoflurane concentration was reduced to 1.5%, the incidence and voltage of the spike waves on electrocorticogram were reduced. When 0.1 mg fentanyl was intravenously administrated during 1.5% sevoflurane anesthesia, the frequency of the spike waves was further reduced. Caution should be taken when using sevoflurane-fentanyl anesthesia because this combination may interrupt identification of epileptic focus on intraoperative electrocorticogram.

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