• Revue médicale suisse · Apr 2011

    [Pulmonary fibrosis and emphysema].

    • Jean-Georges Frey.
    • Centre valaisan de pneumologie, CHCVS, 3963 Crans-Montana.
    • Rev Med Suisse. 2011 Apr 13;7(290):808, 810-2.

    AbstractWe report a case of combined pulmonary fibrosis and emphysema. This syndrome, including upper-lobe emphysema and pulmonary fibrosis of the lower lung was recently described in smokers or ex-smokers (mean age: 65 years). Exertional dyspnea is always present. Pulmonary functions are subnormal while carbon monoxyde transfer is reduced and exercise hypoxemia is present. High resolution CT-scan is key of diagnosis with upper lobes emphysema with diffuse infiltrating fibrosing disease at the bases. Pulmonary hypertension is present is almost 50% of patients, representing the principal negative pronostic factor. Five years survival is 54.6% (median survival 6, 1 years).

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