• Semin. Pediatr. Surg. · May 2013

    Review

    Evidence-based prevention and surgical treatment of necrotizing enterocolitis-a review of randomized controlled trials.

    • Mehul V Raval, Nigel J Hall, Agostino Pierro, and R Lawrence Moss.
    • Division of Pediatric Surgery, Nationwide Children's Hospital, The Ohio State College of Medicine, The Ohio State University, 700 Children's Dr, Columbus, Ohio 43205, USA.
    • Semin. Pediatr. Surg. 2013 May 1;22(2):117-21.

    AbstractNecrotizing enterocolitis remains a common cause of morbidity and mortality in the neonatal period. Despite many advances in the management of the critically ill neonate, the exact etiology, attempts at prevention and determining best treatment for NEC have been elusive. Unfortunately, the overall survival for this poorly understood and complex condition has not improved. NEC is a condition that can and should be studied with randomized prospective trials (RCTs). This chapter reviews the current evidence-based trials for this condition thus far performed.Copyright © 2013 Elsevier Inc. All rights reserved.

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