• Interact Cardiovasc Thorac Surg · Aug 2014

    Long-term results after resection of bronchial carcinoid tumour: evaluation of survival and prognostic factors.

    • Giulio Maurizi, Mohsen Ibrahim, Claudio Andreetti, Antonio D'Andrilli, Anna Maria Ciccone, Leda Marina Pomes, Cecilia Menna, Marianna Pellegrini, Federico Venuta, and Erino Angelo Rendina.
    • Department of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy giuliomaurizi@libero.it.
    • Interact Cardiovasc Thorac Surg. 2014 Aug 1;19(2):239-44.

    ObjectivesWe retrospectively analysed morbidity, mortality and oncological results of patients who had undergone surgery for bronchial carcinoid tumours.MethodsBetween 2002 and 2012, 65 patients with bronchial carcinoids underwent lobectomy (n = 34), sublobar resection (segmentectomy/wedge) (n = 18), sleeve lobectomy (n = 5) (reconstruction of the pulmonary artery was associated in 1 case), sleeve resection of the main bronchus (n = 4) or pneumonectomy (n = 4) (reconstruction of the carina was associated in 1 case).ResultsResection was radical with histologically negative margins in all patients (R0). Histology showed typical carcinoid (TC) in 55 (84.6%) patients and atypical carcinoid (AC) in 10 (15.4%) patients. Final pathological stages were Stage I in 42 (64.6%) patients, Stage II in 18 (27.7%) and Stage III in 5 (7.7%). No postoperative mortality was observed. The postoperative morbidity rate was 15.4% (no bronchial and/or vascular reconstructive-related complications occurred). The median follow-up was 58 (range 2-121) months. The overall recurrence rate was 12.3% (n = 8). The survival rate at 5 years was 100% for TC and 87% for AC. Disease-free survival rates at 3 and 5 years were 95 and 93% for TC and 78 and 44% for AC, respectively (P = 0.004). Pathological nodal involvement (pN1-N2) did not affect overall survival or recurrence.ConclusionsThe surgical treatment of bronchial carcinoids provides high long-term survival rates. Low postoperative morbidity and mortality can be expected even after bronchial reconstruction. The AC appears to be the main factor that determines the risk of recurrence. Bronchial reconstructive lung sparing operations are not related to an increased recurrence rate.© The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

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