• Arch Phys Med Rehabil · Jan 2004

    Randomized Controlled Trial Comparative Study Clinical Trial

    Effects of electric stimulation on C and A delta fiber-mediated thermal perception thresholds.

    • Shea T Palmer, Denis J Martin, Wilma M Steedman, and John Ravey.
    • Queen Margaret University College, Edinburgh, Scotland. spalmer@qmuc.ac.uk
    • Arch Phys Med Rehabil. 2004 Jan 1;85(1):119-28.

    ObjectiveTo determine if interferential current (IFC) or transcutaneous electric nerve stimulation (TENS) alters C and A delta fiber-mediated thermal perception thresholds.DesignSingle-blind, randomized controlled trial.SettingLaboratory.ParticipantsOne hundred forty healthy women volunteers (mean age +/- standard deviation, 20.6+/-2.7 y).InterventionsSubjects were randomly and exclusively assigned to 1 of 7 groups (n=20 in each): 0, 5, and 100 Hz of IFC; 5 and 100 Hz of TENS; placebo and control stimulation. Stimulation was applied through 2 electrodes placed over the median nerve. Warm sensation, cold sensation, hot pain, and cold pain perception thresholds were measured from the thenar eminence by using a quantitative sensory testing device and a method of limits algorithm.Main Outcome MeasuresWarm sensation, cold sensation, hot pain, and cold pain thresholds (degrees C) before, during, and after stimulation.ResultsThere was a statistically significant effect of time for all 4 thermal perception thresholds (separate 2-way analyses of variance with repeated measures, all P<.001). There were no statistically significant differences between experimental groups, nor any interaction effects (all P>.05).ConclusionsNeither IFC nor TENS altered C and A delta fiber-mediated thermal perception thresholds. The results suggest that any analgesic mechanisms with these modalities are likely to be complex.

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