• Paediatric anaesthesia · Jan 1997

    Case Reports

    Unexpected interaction of methylphenidate (Ritalin) with anaesthetic agents.

    • D G Ririe, K L Ririe, N F Sethna, and L Fox.
    • Department of Anesthesia, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27157-1009, USA.
    • Paediatr Anaesth. 1997 Jan 1;7(1):69-72.

    AbstractWe report difficulty with conscious sedation of a child taking methylphenidate for attention deficit disorder and possible delayed adverse interaction of ketamine and methylphenidate resulting in severe nausea, vomiting and dehydration. The effects of methylphenidate and its potential interactions with anaesthetic agents is discussed. We suggest that anaesthesiologists who provide sedation or anaesthesia to patients receiving methylphenidate be aware of the potential need for high sedative doses and the possibility of undesirable interactions.

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