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AACN clinical issues · Feb 1999
ReviewInitial resuscitation after burn injury: therapies, strategies, and controversies.
- K S Ahrns and D R Harkins.
- University of Michigan Trauma Burn Center, Saline 48176, USA.
- AACN Clin Issues. 1999 Feb 1;10(1):46-60.
AbstractThermal injury disrupts normal hemostasis and sets off a cascade of events: cellular alterations and release of inflammatory mediators cause hypovolemic and cellular shock. Fluid resuscitation in burn injuries has been in use for more than a century, and much research has been devoted to development of resuscitation formulas and appropriate choice of fluid. Parameters for adequate monitoring of resuscitation are greatly debated. Current research efforts focus on minimizing burn edema through mediator modulation and on development of definitive endpoints of resuscitation monitoring.
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