• J Indian Med Assoc · Jun 1996

    Renal cortical necrosis in pregnancy-related acute renal failure.

    • J Prakash, K Tripathi, L K Pandey, S R Gadela, and Usha.
    • Division of Nephrology, Institute of Medical Sciences, Banaras Hindu University, Varanasi.
    • J Indian Med Assoc. 1996 Jun 1;94(6):227-9.

    AbstractOf 63 patients of obstetrical acute renal failure, 15 cases (23.8%) had biopsy proven bilateral renal cortical necrosis. Remaining 48 patients (76.2%) had acute tubular necrosis. Eight of 39 cases in early pregnancy had cortical necrosis (postabortum) and 7 of 24 patients in late pregnancy revealed cortical necrosis. Diffuse and patchy cortical necroses were seen in 12 and 3 patients respectively. The incidence of cortical necrosis was almost equal in both early as well as late pregnancies. The high incidence (20.5%) of cortical necrosis following septic abortion remains the interesting feature of the present study in contrast to very low incidence (1.5%) of cortical necrosis in postabortum group in developed countries. The death occurred in most patients (14 ie, 93.3%) of cortical necrosis because of uraemic complications and sepsis.

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