• J Arthroplasty · Dec 2014

    Randomized Controlled Trial

    Intra-articular bupivacaine reduces postoperative pain and meperidine use after total hip arthroplasty: a randomized, double-blind study.

    • Dave W Chen, Chih-Chien Hu, Yu-Han Chang, Mel S Lee, Chee-Jen Chang, and Pang-Hsin Hsieh.
    • Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
    • J Arthroplasty. 2014 Dec 1;29(12):2457-61.

    AbstractOne hundred patients receiving unilateral total hip arthroplasty (THA) were randomized to receive an intra-articular injection of 300mg bupivacaine or normal saline after completion of surgery. Pain scores of the bupivacaine group were significantly lower than those of the control group the first 12hours postoperatively (all, P<0.001). A significantly lower dose of meperidine was used in the study group than in the control group the first 24hours postoperatively (median, 25 vs. 45mg, P<0.001). Nineteen patients in the study group required meperidine the first day after surgery, as compared to 45 patients in the control group. We conclude that intra-articular injection of bupivacaine after THA reduces pain and meperidine use in the first 12hours after surgery.Copyright © 2014 Elsevier Inc. All rights reserved.

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