• Amanda M Baumer, Angela M Clark, David R Witmer, Shirley B Geize, Lee C Vermeulen, and Joseph H Deffenbaugh.
• Department of Pharmacy, The Johns Hopkins Hospital (JHH), Baltimore, MD, USA.
• Am J Health Syst Pharm. 2004 Oct 1;61(19):2015-22.

PurposeThe impact of drug shortages on patient care, the resources used to manage drug shortages, and the cost associated with drug shortages were studied.MethodsA national online survey was conducted to quantify the effects of drug shortages on patient care and pharmacy expenses. Directors of pharmacy in acute care institutions in the ASHP member database were asked to estimate the impact of drug shortages on acquisition costs, pharmacist and nonpharmacist staff time dedicated to specific functions related to drug shortages, and drug-compounding expenses.ResultsUsable responses were received from 370 (24.7%) of 1496 pharmacy directors. Nearly all pharmacy directors surveyed believed that shortages had changed practice, and a majority felt that drug shortages had compromised patient care. Hospital pharmacy personnel devoted a significant amount of time to managing drug shortages. The results suggest that shortages increase the acquisition cost of pharmaceuticals in the United States by over dollar 99 million annually.ConclusionA national survey indicated that drug shortages are having a significant impact on patient care activities and finances in hospitals.

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