• Paediatric anaesthesia · Feb 2003

    Sedation and neuromuscular blockade in paediatric intensive care: a review of current practice in the UK.

    • Stephen D Playfor, David A Thomas, and Imti Choonara.
    • Paediatric Intensive Care Unit, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA, UK. playfor@hotmail.com
    • Paediatr Anaesth. 2003 Feb 1; 13 (2): 147-51.

    BackgroundOur aim was to investigate the current practice of sedation and neuromuscular blockade in critically ill children in paediatric intensive care units (PICUs) in the UK.MethodsA postal questionnaire was sent to all PICUs in the UK.ResultsThe most commonly used sedative agents were midazolam in combination with morphine. Written clinical guidelines for the sedation of critically ill children were available in 45% of units. Sedation is formally assessed in 40% of units. Vecuronium is the most commonly used neuromuscular blocking agent. In the UK, 31% of critically ill children are likely to receive neuromuscular blocking agents. Depth of neuromuscular blockade is routinely assessed in 16% of patients.ConclusionsRelatively few units possess clinical guidelines for the sedation of critically ill children, and only a minority formally assess sedation levels. Where neuromuscular blocking agents are administered, sedation is frequently inadequately assessed and the depth of neuromuscular blockade is rarely estimated.

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