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Randomized Controlled Trial Clinical Trial
Effect of transdermal hyoscine on nausea and vomiting after surgical correction of prominent ears under general anaesthesia.
- P Honkavaara, L Saarnivaara, and U M Klemola.
- Department of Anaesthesia, University of Helsinki, Finland.
- Br J Anaesth. 1995 Jun 1;74(6):647-50.
AbstractIn a double-blind, randomized study, we have compared the efficacy of transdermal hyoscine with placebo in the reduction of nausea and vomiting in 50 patients, ASA I-II, after surgical correction of prominent ears under general anaesthesia. In the placebo group, 28%, 4% and 48% of patients suffered nausea, retching and vomiting, respectively, during the first 24 h after anaesthesia. The corresponding values in the hyoscine group were 12%, 0% and 16% (P < 0.01). In the placebo group more patients (48%) needed droperidol as an antiemetic compared with the hyoscine group (16%; P < 0.05). There was significantly more sedation in the hyoscine group.
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