• Ned Tijdschr Geneeskd · Dec 2007

    Meta Analysis

    [Cinnamon: not suitable for the treatment of diabetes mellitus].

    • N Kleefstra, S J J Logtenberg, S T Houweling, S Verhoeven, and H J G Bilo.
    • Isala klinieken, Diabetes Kenniscentrum, Zwolle. kleefstra@langerhans.com
    • Ned Tijdschr Geneeskd. 2007 Dec 22;151(51):2833-7.

    ObjectiveTo identify published studies evaluating the effects of cinnamon on glycaemic control.DesignLiterature search.MethodThe Medline database was searched using all possible combinations of the words and medical subject headings (MeSH) 'cinnamon', 'diabetes mellitus', 'HbA1C' and 'glucose'. All human or animal studies in which cinnamon was administered as intervention were included.ResultsSeveral animal studies and 5 randomized placebo-controlled trials in humans were found. Most of the animal studies described beneficial effects of cinnamon on glycaemic control. One placebo-controlled trial in patients with type 2 diabetes found that cinnamon intake was associated with favourable effects on fasting plasma glucose. None of the studies reported an improvement in HbA1C. A study in patients with type 1 diabetes found that cinnamon had no effect.ConclusionBased on the currently available evidence, cinnamon should not be recommended for the improvement ofglycaemic control.

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