• Br J Anaesth · Apr 1999

    Randomized Controlled Trial Clinical Trial

    Combined field block and i.p. instillation of ropivacaine for pain management after laparoscopic sterilization.

    • T Callesen, D Hjort, T Mogensen, L Schouenborg, D Nielsen, H Reventlid, and H Kehlet.
    • Department of Anaesthesiology, H:S Hvidovre University Hospital, Denmark.
    • Br J Anaesth. 1999 Apr 1;82(4):586-90.

    AbstractWe have studied the effect of ropivacaine for combined port site and mesosalpinx infiltration, and peritoneal instillation on pain, nausea and vomiting after laparoscopic sterilization, in a double-blind, placebo-controlled study in 80 patients. The total dose of ropivacaine was 285 mg. All patients received intra- and postoperative NSAID in fixed doses. Abdominal and shoulder pain, nausea and vomiting were recorded during the first 8 h after operation and in a diary for 3 days. In the ropivacaine group, abdominal pain scores were lower during the first 4 h (P < 0.00001), additional use of morphine was less (P < 0.001) and fewer patients had nausea or vomiting during the first 72 h (five vs 14; P < 0.05). There were no signs of local anaesthetic toxicity.

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