• J M Loiselle, M D Baker, J M Templeton, G Schwartz, and H Drott.
• Division of Emergency Medicine, Children's Hospital of Philadelphia, Pennsylvania.
• Ann Emerg Med. 1993 Oct 1;22(10):1530-4.

Study ObjectiveTo determine if there is a significant prevalence of drug or alcohol use among adolescents evaluated for significant acute trauma.DesignA prospective, age-matched controlled study over a 20-month period.SettingUrban pediatric emergency department in a Level I pediatric trauma center.ParticipantsPatients between 13 and 19 years of age requiring admission to the trauma service following evaluation in a pediatric ED and an age-matched control group of asthmatic patients.ResultsA total of 134 patients (mean age, 14.8 years) were admitted for trauma-related injuries, and 22 of 65 (34%) were positive for alcohol or drugs of abuse. The mean age of patients with a positive toxicology screen was 15.4 years. Most commonly detected drugs were alcohol (eight), benzodiazepines (eight), cocaine (five), and cannabinoids (four). The number of positive screens in the trauma group (22 of 65) was significantly higher than controls (one of 49) (P < .001). This remained statistically significant even when those trauma patients not screened were assumed to have a negative toxicology screen (22 of 134 versus one of 49) (P < .01). There was also a significantly higher number of positive toxicology screens among adolescents with an intentional versus unintentional mechanism of injury (21 of 71 versus one of 63) (P < .001).ConclusionA significant number of adolescents admitted to the hospital for trauma-related injuries have a toxicology screen positive for alcohol or drugs of abuse. A toxicology screen should be a standard laboratory test in adolescents involved in significant trauma, especially if the mechanism was intentional.

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