• Experimental neurology · Jan 2010

    The fascination of complex regional pain syndrome.

    • Wilfrid Jänig.
    • Physiologisches Institut, Christian-Albrechts-Universität zu Kiel, Kiel, Germany. w.janig@physiologie.uni-kiel.de
    • Exp. Neurol. 2010 Jan 1;221(1):1-4.

    AbstractComplex regional pain syndrome (CRPS) is a pain disorder involving the somatosensory, the somatomotor and the sympathetic nervous systems. Based on experiments conducted by Bove (2009), it is suggested that changes in impulse activity in small-diameter afferents and postganglionic axons generated by neuritis can contribute to signs of early CRPS. The potential mechanisms involved are discussed. These mechanisms include the possibility that CRPS, a disorder of the central nervous system, may be caused by a nerve inflammation.

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