• Perfusion · Mar 2009

    Case Reports

    Bioline heparin-coated ECMO with bivalirudin anticoagulation in a patient with acute heparin-induced thrombocytopenia: the immune reaction appeared to continue unabated.

    • F Pappalardo, G Maj, A Scandroglio, F Sampietro, A Zangrillo, and A Koster.
    • Department of Cardiovascular Anesthesia and Intensive Care, Vita-Salute University, IRCCS San Raffaele Hospital, Milan, Italy. pappalardo.federico@hsr.it
    • Perfusion. 2009 Mar 1;24(2):135-7.

    AbstractHeparin-induced thrombocytopenia (HIT) is a serious, antibody-mediated complication of heparin which significantly confers risks of thrombosis and devastating outcomes. Once diagnosed, it requires immediate cessation of heparin and therapy with an alternative anticoagulant. No data are available in the literature on the pathophysiology and clinical implications of performing prolonged extracorporeal membrane oxygenation with a heparin-coated system in a patient with acute HIT treated with bivalirudin.

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