• Radiother Oncol · Aug 2008

    Comparative evaluation of radiochemotherapy with temozolomide versus standard-of-care postoperative radiation alone in patients with WHO grade III astrocytic tumors.

    • Stephanie E Combs, Monika Nagy, Lutz Edler, Renate Rausch, Marc Bischof, Thomas Welzel, Jürgen Debus, and Daniela Schulz-Ertner.
    • University Hospital of Heidelberg, Department of Radiation Oncology, Heidelberg, Germany. Stephanie.Combs@med.uni-heidelberg.de
    • Radiother Oncol. 2008 Aug 1;88(2):177-82.

    AbstractOutcome after radiochemotherapy (RCHT) with temozolomide (TMZ) versus radiotherapy (RT) for WHO grade III astrocytic tumors was evaluated. No significant difference in overall survival or progression-free survival between both groups was calculated. RCHT seems not to result in an improved outcome. Further randomized studies are needed to support these results.

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