• Joong Sik Eom, Mi-Suk Lee, Hee-Kyung Chun, Hee Jung Choi, Sun-Young Jung, Yeon-Sook Kim, Seon Jin Yoon, Yee Gyung Kwak, Gang-Bok Oh, Min-Hyok Jeon, Sun-Young Park, Hyun-Sook Koo, Young-Su Ju, and Jin Seo Lee.
• Division of Infectious Diseases, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.
• Am J Infect Control. 2014 Jan 1;42(1):34-7.

BackgroundFor prevention of ventilator-associated pneumonia (VAP), a bundle approach was applied to patients receiving mechanical ventilation in intensive care units. The incidence of VAP and the preventive efficacy of the VAP bundle were investigated.MethodsA quasi-experimental study was conducted in adult intensive care units of 6 university hospitals with similar VAP rates. We implemented the VAP bundle between March 2011 and June 2011, then compared the rate of VAP after implementation of the VAP bundle with the rate in the previous 8 months. Our ventilator bundle included head of bed elevation, peptic ulcer disease prophylaxis, deep venous thrombosis prophylaxis, and oral decontamination with chlorhexidine 0.12%. Continuous aspiration of subglottic secretions was an option.ResultsImplementation of the VAP bundle reduced the VAP rate from a mean of 4.08 cases per 1,000 ventilator-days to 1.16 cases per 1,000 ventilator-days. The incidence density ratio (rate) was 0.28 (95% confidence interval, 0.275-0.292).ConclusionsImplementing the appropriate VAP bundle significantly decreased the incidence of VAP in patients with mechanical ventilation.Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

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