• Headache · Feb 2016

    Review

    The Sphenopalatine Ganglion: Anatomy, Pathophysiology, and Therapeutic Targeting in Headache.

    • Matthew S Robbins, Carrie E Robertson, Eugene Kaplan, Jessica Ailani, Larry Charleston, Deena Kuruvilla, Andrew Blumenfeld, Randall Berliner, Noah L Rosen, Robert Duarte, Jaskiran Vidwan, Rashmi B Halker, Nicole Gill, and Avi Ashkenazi.
    • Montefiore Headache Center, Bronx, NY, USA.
    • Headache. 2016 Feb 1; 56 (2): 240-58.

    AbstractThe sphenopalatine ganglion (SPG) has attracted the interest of practitioners treating head and face pain for over a century because of its anatomical connections and role in the trigemino-autonomic reflex. In this review, we discuss the anatomy of the SPG, as well as what is known about its role in the pathophysiology of headache disorders, including cluster headache and migraine. We then address various therapies that target the SPG, including intranasal medication delivery, new SPG blocking catheter devices, neurostimulation, chemical neurolysis, and ablation procedures. © 2015 American Headache Society.

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