• Indian J Med Sci · Mar 2006

    Case Reports

    Pregnancy in a patient of Glanzmann's thrombasthenia.

    • Neena Malhotra, Charu Chanana, and Deepika Deka.
    • Department of gynecology and obstetrics,All India Institute of medical sciences, New Delhi, India. charuchanana@rediffmail.com
    • Indian J Med Sci. 2006 Mar 1;60(3):111-3.

    AbstractGlanzmann's thrombasthenia is a congenitally acquired platelet disorder with an autosomal recessive mode of inheritance. Though, quantitatively normal, the aggregation ability of platelets is reduced in this condition. Pregnancy and delivery are rare in these patients and have been associated with a high risk of severe post-partum hemorrhage. We describe a primigravida, who was diagnosed to have Glanzmann's thrombasthenia during adolescence. She developed secondary post-partum hemorrhage after an elective caesarean section, which was successfully managed by single donor platelet transfusion.

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