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Case Reports
Epidural anaesthesia, ephedrine and phenylephrine in a patient taking moclobemide, a new monoamine oxidase inhibitor.
- J W Martyr and C E Orlikowski.
- Department of Anaesthetics, King Edward Memorial Hospital, Subiaco, Perth, Australia.
- Anaesthesia. 1996 Dec 1;51(12):1150-2.
AbstractWe report a case of low thoracic epidural and general anaesthesia in a patient receiving moclobemide, a new selective inhibitor of monoamine oxidase A. Intra-operative hypotension was initially treated with phenylephrine and then with ephedrine. The short half-life of moclobemide and its modest interaction with direct and indirect acting sympathomimetic drugs permit the use of epidural anaesthesia, since any associated hypotension can be safely treated.
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